TotalBiscuit will stop playing WoW and will also stop doing the show.
I was not a regular watcher of his show, but he has a way of talking that makes it easy to listen to him. I recommend watching the last show, linked above. It's mostly a long rant on why he leaves.
I don't think it is especially revelatory, by the way. 50% of what he says is some unreflected mishmash, the other 50% are not really insightful. But that doesn't change the fact that a famous player leaves and I am pretty sure that is not going unnoticed at Blizzard.